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KMID : 0385020010170010035
Korean Journal of Laboratory Animal Science
2001 Volume.17 No. 1 p.35 ~ p.46
Distribution of endocrine cells in pancreas of postnatal Mongolian gerbil







Abstract
The regional distribution, population and shape of pancreatic endocrine cells in postnatal mongolian gerbil were studied using immunohistochemical method. In the early pancreas(day 1 and day 10), the islet in head region were less developmented than in tail region. In these immunohistochemical observations, insulin immunoreactive cells were located throughout the islet and the more abundant than other endocrine cells, through all ageing. Immunoreactive cells of glucagon, pancreatic polypeptide and somatostatin, however, were found in peripheral region of islet, which was consistent with other animals. Pancreatic polypeptide immnoreactive cells were more abundant in infant than in adult, the somatostatin(D-cells), however, were more in adult. These results differed from other animals. These observation can be provided many basic information for further studies regarding the mechanisms and factors that control both the growth and the differentiation of endocrine cell populations in several laboratory animals.
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